SEEHRA, JASBIR,PEARSALL, ROBERT SCOTT,KUMAR, RAVINDRA
申请号:
CA2770822
公开号:
CA2770822C
申请日:
2010.08.13
申请国别(地区):
CA
年份:
2020
代理人:
摘要:
Compositions for increasing red blood cell levels or treatment of anemia comprising erythropoietin receptor activators and a variant Activin RIIB (ActRIIB) polypeptide having a leucine residue replaced by a acidic amino acid residue, where the variant ActRIIB polypeptide has a reduced affinity for activin B and may be called a GDF trap. Methods for the use of these compositions.