WU, MING DER,吴明德,吳明德,CHENG, MING JEN,郑铭仁,鄭銘仁,CHEN, YEN LIN,陈彦霖,陳彥霖,CHEN, SIAO JHEN,陈校祯,陳校禎,YU, LI WEN,余立文,HSU, HSUN YIN,许薰尹,許薰尹
申请号：
TW105140650
公开号：
TW201720441A
申请日:
2016.12.08
申请国别(地区):
TW
年份:
2017
代理人:
摘要：
A method for inhibiting xanthine oxidase and for reducing uric acid levels using a beta-carboline alkaloid compound of formula (I), wherein R1 is selected from the group consisting of a carboxyl group, a carboxylate group, a carboxamide group and hydrogen, and R2 is selected from the group consisting of -CH2COOCH3, a methoxy group, hydrogen and a methyl group. Also disclosed is a method for monitoring xanthine oxidase inhibiting activity level.本案揭示一種使用式(I)之β-咔啉生物鹼化合物來抑制黃嘌呤氧化酶及降低尿酸含量的方法，其中R1選自由羧基、羧酸酯基、羧醯胺基及氫組成之群，且R2選自由-CH2COOCH3、甲氧基、氫及甲基組成之群。亦揭示一種用於監測黃嘌呤氧化酶抑制活性程度的方法。
