Michael Bardroff,Bernd Bohrmann,Manfred Brockhaus,Walter Huber,Titus Kretzschmar,Hansruedi Loetscher,Corinna Löhning,Christer Nordstedt,Christine Rothe
申请号：
US12462119
公开号：
US08216577B2
申请日:
2009.07.28
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to antibody molecules capable of specifically recognizing two regions of the β-A4 peptide, wherein the first region comprises the amino acid sequence AEFRHDSGY as shown in SEQ ID NO: 1 or a fragment thereof and wherein the second region comprises the amino acid sequence VHHQKLVFFAEDVG as shown in SEQ ID NO: 2 or a fragment thereof. Furthermore, nucleic acid molecules encoding the inventive antibody molecules and vectors and hosts comprising said nucleic acid molecules are disclosed. In addition, the present invention provides for compositions, preferably pharmaceutical or diagnostic compositions, comprising the compounds of the invention as well as for specific uses of the antibody molecules, nucleic acid molecules, vectors or hosts of the invention.
