BODMEIER ROLAND,CARMODY ALAN FRANCIS,CIPER MESUT,DE PAEPE ANNE THERESE GUSTAAF,FEEDER NEIL,HEIMLICH JOHN MARK,KORBER MARTIN,WALTHER MATHIAS
申请号：
NZ61303112
公开号：
NZ613031A
申请日:
2012.01.17
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Provided is a solid dispersion comprising 3:97 to 12:88 weight percentage ratio of fesoterodine hydrogen fumarate: an alkyl hydroxyalkylcellulose ether or a hydroxyalkylcellulose ether or an ester thereof or a mixture of any two or more. Fesoterodine hydrogen fumarate can be stabilised in the dispersion in a form not corresponding to its crystalline or amorphous form. A preferred cellulose ether component is hydroxypropyl methyl cellulose. Further provided is an inert core bead or particle coated with the dispersion, optionally with a modified-release coating on the bead or particle, and a capsule or tablet comprising the beads or particles. The dispersion may be used in the treatment of urinary incontinence.
