ХАКНИ Джейсон А. (US),КЕИР Мэри (US),ТЬЮ Гаик Вен (US)
申请号:
RU2016136716
公开号:
RU2016136716A
申请日:
2015.03.26
申请国别(地区):
RU
年份:
2018
代理人:
摘要:
Biomarkers predictive of responsiveness to integrin beta7 antagonists, including anti-beta7 integrin subunit antibodies, and methods of using such biomarkers are provided. In addition, methods of treating gastrointestinal inflammatory disorders such as inflammatory bowel diseases including ulcerative colitis and Crohn's disease are provided. Also provided are methods of using such predictive biomarkers for the treatment of inflammatory bowel diseases including ulcerative colitis and Crohn's disease.