Olaf Schneewind,Alice G. Cheng,Dominique M. Missiakas,Hwan Keun Kim,Hye-Young Kim
申请号:
US13821943
公开号:
US20130230550A1
申请日:
2011.09.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by a Staphylococcus bacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.