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機能性高分子皮膜で被覆された高含量薬物粒子およびそれを含む錠剤ならびにそれらの製造方法
专利权人:
全星薬品工業株式会社
发明人:
林田 知大,山崎 淳治,中野 善夫,樋崎 雅也,木下 直俊
申请号:
JP2014553568
公开号:
JP5758552B2
申请日:
2013.05.08
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
Provided are functional drug-containing particles which can be compressed into tablets and in particular, to orally disintegrating tablets by employing any of a dry molding method, a wet molding method, or a humidifying drying method. The functional drug-containing particles comprise substantially spherical drug-containing particles essentially including drug and a binder, the functional drug-containing particles including a functional polymer film selected from the group consisting of an enteric film, a release control film, and a bitter taste masking film, an average particle diameter of said functional drug-containing particles being 400 µm or less, a particle diameter ratio D 90 /D 10 of the functional drug-containing particles with respect to particle size distribution calculated on a volumetric basis being 1.65 or more, or a coefficient of variation in particle diameters being 24% or more.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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