Method for predicting prognosis of small cell lung cancer using miRNA, method for treating small cell lung cancer, method for improving prognosis of small cell lung cancer, and method for screening agent for treating small cell lung cancer
The present invention provides a prognosis method for small cell lung cancer, a method for treating small cell lung cancer, a method for improving prognosis of small cell lung cancer, a therapeutic agent for small cell lung cancer, and a screening method for a therapeutic agent for small cell lung cancer using miRNA. Specifically, the present invention relates to a method for prognosing a small cell lung cancer patient using miR-153, miR-196a, miR-203 or miR-216a as an index, a method for improving the prognosis of a small cell lung cancer using them, and A small cell lung cancer therapeutic method and a small cell lung cancer therapeutic agent targeting the above, and a screening method for a small cell lung cancer therapeutic agent using the same.本発明は、ｍｉＲＮＡを用いた小細胞肺癌の予後診断方法、小細胞肺癌治療方法、小細胞肺癌予後改善方法、小細胞肺癌治療剤及び小細胞肺癌治療薬のスクリーニング方法を提供する。具体的には本発明は、ｍｉＲ－１５３、ｍｉＲ－１９６ａ、ｍｉＲ－２０３又はｍｉＲ－２１６ａを指標とした小細胞肺癌患者の予後の診断方法、それらを指標とした小細胞肺癌予後改善方法、それらをターゲットとした小細胞肺癌治療方法及び小細胞肺癌治療剤、それらを使用した小細胞肺癌の治療剤のスクリーニング方法を提供する。
