William H. Frey, II,Samuel Scott Panter,Leah Ranae Bresin Hanson
申请号:
US14068561
公开号:
US09636313B2
申请日:
2013.10.31
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Methods for treating the animal central nervous system against the effects of spinal cord injury, including associated cognitive, behavioral and physical impairments. Effective amounts of therapeutic agents are administered to the upper third of the patients nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and/or copper such as iron chelators, copper chelators, and antioxidants. A particular example of a therapeutic agent is the iron chelator deferoxamine (DFO).