A method for evaluating an aerosolized test compound includes administering a test compound to a first population of individuals, via inhalation of an aerosol； administering a placebo comprising riboflavin 5′-phosphate to a second population of individuals, via inhalation of an aerosol； and comparing a biological marker for the individuals in the two populations. An aerosol comprising riboflavin 5′-phosphate (also known as flavin mononucleotide) may be used either as a placebo in clinical trials, or therapeutically.
