Pharmaceutical composition for the treatment of cancer related fgfr4, fgf19 related cancer or liver cancer positive for gene amplification fgf19.A pyrimidine Compound has a specific inhibitory Action on fgfr4, and a Pharmaceutical composition with the compound as an active ingredient is an effective treatment of cancer related fgfr4； another form of realization, fgf19 related cancer, and au No other form of realization, Liver Cancer positive for gene amplification fgf19.Claim 1: a Pharmaceutical composition for the treatment of cancer related fgfr4, comprising 5 - [(2.6 - difluoro - 3.5 - dimetoxibencil) oxy] - n {- 3 - methoxy - 4 - [4 - (metilpiperazin - 1 - il) piperidin-1-yl] phenyl pyrimidine 2} - Amine ({2 - [4 - [5 - (2,6 - difluoro - 3.5 - dimetoxibencil) oxy] - 2 - (pyrimidin-2-yl L} amino) - 1H pyrazol-1-yl] ethanol, (2R) - 3 - [4 - [({5 (2.6 - difluoro - 35dimetoxibencil) oxy] amino} - 2 - il pyrimidin-2-yl) - 1H pyrazol-1-yl] propane-1,2-diol, 5 - [(2.6 - difluoro - 3.5 - dimetoxibencil) oxy] - N - [4 - (metilpiperazin - 1 - il) phenyl] - 2 - or Amine pyrimidine 5 - [(2.6 - difluoro - 3.5 - dimetoxibencil) oxy] - N - (1 - methyl - 5 - [(4 metilpiperazin - 1 - yl) methyl] - 1hpirazol il} - 3 - 2 - Amine pyrimidine, or a Pharmaceutically acceptable salts thereof, and an excipient.Claim 2: the pharmaceutical composition according to claim 1, wherein the cancer related to fgfr4 is fgf19 related cancer. Claim 3: the pharmaceutical composition according to claim 1, wherein the fgfr4 related cancer is cancer of the Liver fgf19 positive for gene amplification.Composición farmacéutica para el tratamiento de cáncer relacionado con FGFR4 ,cáncer relacionado con FGF19, o cáncer de hígado positivo para la amplificación del gen FGF19. Un compuesto de pirimidina específico tiene una acción inhibitoria sobre FGFR4, y una composición farmacéutica que tiene el compuesto como un ingrediente activo tiene un efecto de tratamiento de cáncer relacionado con FGFR4； en otra form
