The present invention provides methods and compositions for treating non-small-cell lung cancer (NSCLC) by administering a) a composition comprising nanoparticles that comprise paclitaxel and an albumin and b) a platinum-based agent (e.g., carboplatin). The present application also provides methods of treating prostate cancer by administering to the individual a) an effective amount of a composition comprising nanoparticles comprising docetaxel and an albumin； and b) an effective amount of a steroid.本發明提供用於治療非小細胞肺癌(NSCLC)之方法及組合物，其藉由投與a)包含含有太平洋紫杉醇(paclitaxel)及白蛋白之奈米粒子的組合物及b)鉑基藥劑(例如卡鉑(carboplatin))來進行。本發明亦提供治療前列腺癌之方法，其藉由向個體投與a)有效量之包含含有多西他賽(docetaxel)及白蛋白之奈米粒子的組合物；及b)有效量之類固醇來進行。
