Medicinal plants play a key role in the human health care. About 80% of the world populations rely on the use of traditional medicine. This is predominantly based on plant materials. Plant extracts for liver diseases should possess sufficient efficacy to cure severe liver disease caused by toxic chemicals, Viruses, excess alcohol intake. Effective formulations have to be developed using medicinal plants. Phyllanthus acidus and Parkia javanica are tropical plants that are consumed as herbs by the Indian tribal for remedy of gastrointestinal tract disorders. We have tried to establish whether they have any immune modulatory effects on the micro phases for an enhanced immune action. Phyllanthus sps. Has long been used in folk medicine in many countries as antimicrobial and / or antioxidants our finding support the uses of the phyllanthus species in traditional medicine. Physalis minima Linn. Is widely used in the indigenous system of medicine for the treatment of diuretic, fevers, dropsy, etc., In the present study an attempt to evaluate phytochemical constituents and anti hepatica activity of the leaf and unripe fruit of P.minima. All part of the Physalis minima has identified triterpenoid substances. Former identified terpenoid such as geranio was shown to inhibit the growth of hepatic carcinoma cells. In this present study phytochemical constitution pharmogonestic studies, Antioxidant activity and cytotoxicity assay of the two plants Phyllanthus acidus and Physalis minima. Adult male albino rats were used for Anti-hepatitis assay for the determination of HBS Ag, HBE Ag, HBV DNA, Plasmid construction & HBV promoter Luciferacea reporter assay. Finally compound were isolated from leaf or fruit to cure or protect hepatitis. And also structural elucidiation of the compound is found out.
