ANTIBODIES THAT RECOGNIZE IAPP

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专利权人:

PROTHENA BIOSCIENCES LIMITED

发明人:

Robin Barbour,Yue Liu

申请号：

US15816860

公开号：

US20180171011A1

申请日:

2017.11.17

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention provides monoclonal antibody 6B8 and related antibodies. The 6B8 antibody binds to an epitope within residues 3-12 of IAPP. The antibodies of the invention are useful, for example, for treating disorders associated with IAPP accumulation, particularly accumulation of IAPP deposits. Such disorders include type 2 diabetes, metabolic syndrome, impaired insulin tolerance, impaired glucose tolerance, insulinomas, and related conditions.

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