INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY ASCR; V.V.I.
发明人:
BIRKUS, GABRIEL,PAV, ONDREJ,ROSENBERG, IVAN,SIMAK, ONDREJ
申请号：
CA3093888
公开号：
CA3093888A1
申请日:
2019.04.04
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to 3'3'-cyclic dinucleotides modified with a 3'-phosphonoalkyl bond and derivatives thereof, that can modulate the activity of the STING adaptor protein (I) or a pharmaceutically acceptable salt thereof wherein L1 is -O- or -K-C(R6R7)-； L2 is -K-C(R6R7)-.
