Margaret A. Shipp,Stefano Monti,Bjoern Chapuy,Scott J. Rodig,Todd R. Golub
申请号:
US14381004
公开号:
US09890429B2
申请日:
2013.02.28
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating cancer (e.g., hematological malignancies in humans). A variety of biomarker chromosomal number alterations (CNAs) and biomarkers corresponding thereto, are provided, wherein alterations in the copy number of one or more of the biomarker CNAs and/or alterations in the amount, structure, and/or activity of one or more of the biomarkers comprised within the CNAs is associated with cancer status.