COMPOSITIONS AND METHODS FOR MODULATING TOLL LIKE RECEPTOR SIGNAL

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专利权人:

CASE WESTERN RESERVE UNIVERSITY

发明人:

M. Edward Medof,Jinbo Liu,Michael G. Strainic

申请号：

US15974307

公开号：

US20180256646A1

申请日:

2018.05.08

申请国别(地区):

US

年份:

2018

代理人:

摘要：

A method of method of inhibiting Toll like receptor (TLR) signaling in dendritic cells (DCs) of a subject in need thereof includes administering at least one complement antagonist to the DCs at an amount effective to substantially inhibits C3a receptor (C3aR) and/or C5a receptor (C5aR) signal transduction in the DCs induced by TLR signaling.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/