Compositions and methods for inhibiting the interaction between cftr and cal

• 收藏
• 分享

专利权人:

TRUSTEES OF DARTMOUTH COLLEGE

发明人:

MADDEN DEAN R.,CUSHING PATRICK R.,BOISGUERIN PRISCA,VOLKMER RUDOLF,VOUILLEME LARS

申请号：

NZ62597012

公开号：

NZ625970A

申请日:

2012.11.05

申请国别(地区):

NZ

年份:

2016

代理人:

摘要：

Discloses an agent comprising the amino acid sequence of (L/A)-(Q/P/F)-T-(S/T)-(K/I)-I, or a derivative or peptidomimetic thereof, and use of an agent comprising the amino acid sequence of (L/A)-(Q/P/F)-(S/T)-(S/T)-(K/I)-I in the manufacture of a medicament to prevent or treat cystic fibrosis, wherein the peptide selectively inhibits the interaction between a degradation-prone Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and CFTR-Associated Ligand.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/