Composés et compositions en tant que modulateurs de la voie Hedgehog

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专利权人:

NOVARTIS AG

发明人:

申请号：

EP11165059.4

公开号：

EP2363393B1

申请日:

2007.05.04

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention provides a method for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula I.

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中国工程科技知识中心

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