BLATTNER, CRISTOPHER R.,FRISCH, DAVID A.,NOVY, ROBERT E.,HENKER, TERRANCE M.,STEFFEN, ERIC A.,BLATTNER, FREDERICK R.,CHOI, HYUNSIC,POSFAI, GYORGY,LANDRY, CHARLES F.
申请号：
CA2940316
公开号：
CA2940316A1
申请日:
2015.03.02
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Rediced genome or native K12 strain E. coli bacteria comprising expression vectors encoding a recombinant CRM197 protein and their use in the production of CRM 197 is provided. The CRM 197 protein may be fused to a signal sequence that directs the expressed CRM197 protein to the periplasm of the E. coli host.
