GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION
发明人:
PARK, JUNG HWANKR,박정환,AHN, MYUN HWANKR,안면환,HAN, MEE REEKR,한미리
申请号：
KR1020140053907
公开号：
KR1020150127876A
申请日:
2014.05.07
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a micro-bullet for drug delivery, which is a bullet containing a drug and is separated from a base by external force to be injected into the skin. The micro-bullet according to the present invention can be separated from the base, thus only a bullet can be inserted into the skin, allowing a desirable fixed amount of a drug to be injected without loss. In addition, the micro-bullet according to the present invention can allow the injection depth to be changed depending on the magnitude of force. While conventional transdermal delivery systems require long time to inject, the present invention can quickly deliver a desirable amount of a drug within a short time in few seconds into the skin. The micro-bullet according to the present invention can have a drug inserted thereinto, and can control the emission speed and amount of a drug depending the size of a bullet, the degeneration speed of a bullet, and the like. The micro-bullet according to the present invention is arranged so that a bullet is attached onto the base, and a bullet is separated as soon as being injected into the skin by external force, thereby 1) allowing hundreds or thousands of bullets to be delivered by one-time external force, and 2) thus delivering transdermal dose delivery for a few to tens of milligrams or more of a drug. Moreover, a bullet is attached onto the base and is handled with a film-shaped base to provide convenient handling the film-shaped base allows ease connection to conventional patch formulations, and requires no complex equipment such as a cylinder to inject a bullet and only external force is necessary to separate a bullet from the base so as to provide a simple force transfer system.COPYRIGHT KIPO 2016본 발명은 약물을 함유하는 총알이 외부 힘에 의해 베이스로부터 분리되어 피부에 삽입되는 약물 전달용 마이크로 총알에 관한 것이다. 본 발명의 마이크로 총알은 베이스로부터 총알만이 피부 내부에 삽입될 수 있어 원하는 양의 약물을 손실 없이 정량 투여할 수 있다. 또한, 본 발명의 마이크로 총알은 전달하는 힘의 크기에 따라 총알의 투여 깊이를 제어할 수 있다. 본 발명은 기존의 경피 전달 시스템이 오랜 투여 시간을 필요로 하는것에 반해 수초내
