Suixiong CAI,Ye Edward TIAN,Zhiqiang DONG,Xiaozhu WANG
申请号:
US16629185
公开号:
US20200131192A1
申请日:
2018.07.10
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are imidazo[1,2-b]pyrimido[4,5-d]pyridazin-5(6H)-one compounds, specifically represented by the Formula I:or a pharmaceutically acceptable salt or prodrug thereof, wherein A and R1-R5 are defined herein. Compounds having Formula I are Wee1 kinase inhibitors. Therefore, compounds of the disclosure may be used to treat diseases caused by abnormal Wee1 activity.