CHOI JI WON U K,GODWIN ANTHONY U K,PAWLISZ ESTERA U K
申请号：
IN10063/DELNP/2011
公开号：
IN2011DN10063A
申请日:
2011.12.20
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
A process for the conjugation of a polymer to a protein, which comprises reacting a polymeric conjugating agent with said protein, in an aqueous medium, in the presence of an amphipathic sugar polymer. The process is particularly useful when conjugation PEG to proteins, particularly to proteins with have previously proved difficult to PEGylate in acceptable yields, for example INF -ß.
