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変性病変の診断のためのリガンドとしてのフコイダン
专利权人:
ユニヴェルシテ パリ 13
发明人:
ミシェル,ジャン-バティスト,ルトゥールヌール,ディディエ,ショーベ,フレデリク,バシュレ,ロール,ルーゼ,フランソワ,ミュールマン,アラン
申请号:
JP2014097393
公开号:
JP6099055B2
申请日:
2014.05.09
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a diagnosis method of clinical symptoms characterized by a detection of selectin and an undesirable and/or unusual selectin expression.SOLUTION: The invention relates to a selectin targeting imaging agent which contains at least one fucoidan portion associated with at least one detectable potion, and to a method and a kit using the imaging agent, which are used for diagnosis of clinical symptoms, such as thrombosis, myocardial ischemia/reperfusion injury, a stroke and an ischemia brain trauma, neurodegenerative disorder, tumor metastasis and tumor growth, and rheumatoid arthritis. The imaging agent is detectable by ultrasonography, Magnetic Resonance Imaging (MRI), Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT), fluorescence spectroscopy, computed tomography, X-ray radiography, or any combination thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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