PRUITT, JOHN DALLAS,WINTERTON, LYNN COOK,NELSON, JARED
申请号:
NZ60060909
公开号:
NZ600609A
申请日:
2009.12.03
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a process for making a soft silicone hydrogel contact lens capable of gradually delivering a hydrophobic comfort agent during wearing of the contact lens. a) dipping a soft silicone hydrogel contact lens in a solution containing a hydrophobic comfort agent and an organic solvent miscible with water, wherein the soft hydrogel contact lens comprises a polymer matrix including hydrophobic units derived from a silicone-containing monomer or macromer and/or a hydrophobic monomer and hydrophilic units derived from a hydrophilic monomer or macromer, wherein the hydrophobic comfort agent comprises a phospholipid, a monoglyceride, a diglyceride, a triglyceride, a glycolipid, a glyceroglycolipid, a sphingolipid, a sphingo-glycolipid, in or any mixture thereof, b) hydrating the soft silicone hydrogel contact lens having the comfort agent distributed therein in water or a buffered aqueous solution to replace the organic solvent with water or the aqueous solution; and c) placing and sealing the hydrated soft hydrogel contact lens in a lens package containing a lens packaging solution, wherein the soft contact lens is characterized by its capability of gradually releasing the hydrophobic comfort agent from the polymer matrix into the eye of a wearer when being worn.