In one aspect of the present invention, this medicine storage cartridge (20) with a nozzle is provided with: a medicine container (21) filled with a predetermined amount of a powdered medicine; a nozzle part (22) that is formed in the medicine container (21) and sprays the powdered medicine; a closing member (24) for closing an opening (22a) of the nozzle part (22); and a valve member (25) that functions as a stopper for closing another opening (23a) of the medicine container (21) and opens when the medicine is administered. The medicine storage cartridge (20) can be detachably attached to a sprayer (30) when the medicine is administered.