In one aspect of the invention, a medical fluid pumping system and method of pumping medical fluid are provided. The medical fluid pumping system includes a medical fluid pump chamber. A fluid exchange conduit is fluidly coupled to the medical fluid pump chamber. At least one pump configured to pump medical fluid to and drain medical fluid from a cavity of a patient via a patient line is coupled to the fluid exchange conduit. A pump controller is communicably coupled to the at least one pump. The pump controller is configured to cause the pump to transmit fluid pulses.
