Wen-Lian Wu,Duane A. Burnett,Andrew W. Stamford,Jared N. Cumming,Chad E. Bennett,Eric J. Gilbert,Jack D. Scott,Younong Yu,Xuanjia Peng
申请号：
US14110363
公开号：
US20140128382A1
申请日:
2012.04.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention discloses certain iminothiazine compounds and mono- and dioxides thereof, including compounds Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomers and said stereoisomers, wherein each of variables shown in the formula are as defined herein. The compounds of the invention may be useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and uses, including Alzheimers disease, are also disclosed.
