THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
PASQUALINI, RENATA,ARAP, WADIH,GELOVANI, JURI,MARINI, FRANK C., III,HAJITOU, AMIN,ALAUDDIN, MIAN,TREPEL, MARTIN
申请号:
CA2649182
公开号:
CA2649182C
申请日:
2007.04.09
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Embodiments of the invention are generally directed to compositions and methods of delivering one or more transgene to a target cell, such as a tumor cell, in a site-specific manner to achieve enhanced expression and to constructs and compositions useful in such applications. In certain aspects, expression from a therapeutic nucleic acid may be assessed prior to administration of a treatment or diagnostic procedure to or on a subject.