The invention relates to an use of a JAK kinase inhibitor in combination with an EGFR inhibitor for a preparation of a medicament for treating tumor diseases. In particular, the invention relates to an use of a JAK kinase inhibitor in combination with an human epidermal growth factor receptor inhibitor for a preparation of a medicament for preventing or treating tumor diseases.本發明關於JAK激酶抑制劑與EGFR抑制劑聯合在製備治療腫瘤疾病的藥物中的用途。具體而言,本發明關於一種JAK激酶抑制劑與人表皮生長因子受體抑制劑(EGFRi)聯合在製備預防或治療腫瘤疾病的藥物中的用途。