Kai Licha,Michael Schirner,Pia Welker,Rainer Haag,Marie Weinhart,Florian Paulus
申请号:
US13576779
公开号:
US08877171B2
申请日:
2011.01.31
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations.