Mudd, Christopher S.,Stroumpoulis, Dimitrios,Tezel, Ahmet
申请号:
AU2008331602
公开号:
AU2008331602B2
申请日:
2008.11.24
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Described herein are polysaccharide gel formulations including at least oneinhibitor of polysaccharide degradation and methods of making the same. Themethods described herein involve the steps of providing at least one polysaccharideand incorporating at least one inhibitor of degradation into the polysaccharide.In some embodiments, the incorporating step comprises 1 ) mixing the at leastone inhibitor with the at least one polysaccharide at a highly hydrated statethereby encapsulating the at least one inhibitor in a polysaccharide network,and 2) dehydrating the polysaccharide network thereby controlling releasekinetics or final swell ratio. In another embodiment, the incorporating stepcomprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradablevessel and 2) combining the polysaccharide and the vessel into a gel formulation.The polysaccharide gel formulations described herein can be used for a varietyof cosmetic applications.