The invention provides a drug for external use with a hypoglycemic effect, which has remarkable hypoglycemic effect, effectively prevents and treats diseases such as diabetes. Patients using the drug are weakly resistant to the drug. Cochinchina momordicae seed, pharbitis seed, astragalus, tortoise plastron, liquorice, schisandrae chinensis, rehmanniae, atractylodes japonica, radix pseudostellariae, malaytea scurfpea, gingko and white pepper are mixed in a weight ratio of 28.2:23.5:9.4:7.1:2.4:4.7:4.7:4.7:4.7:4.7:4.7:1.2, then the mixture is mixed with the white of an unfertilized egg. The resultant is fixed in the middle of the sole of foot and wetly applied for 15 hours.
