Jay A. White,Samir P. Tabash,Sammy A. Agudoawu,Joel Z. Melnick
申请号:
US16448838
公开号:
US20190374555A1
申请日:
2019.06.21
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A stabilized formulation for controlled release of a vitamin D compound is disclosed. The formulation comprises one or both of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 and a cellulosic compound. The stabilized formulations exhibit a stable dissolution profile following exposure to storage conditions and demonstrate improved pharmacokinetic parameters compared to unstabilized formulations.