Polypeptide inhibitors of urokinase type plasminogen activator

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专利权人:

发明人:

申请号：

EP11250671.2

公开号：

EP2420255A2

申请日:

2011.07.22

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

A conjugate which is capable of specific binding to and inhibition of urokinase-type plasminigen activator (UPA) comprising a polypeptide molecule and a scaffold molecule,wherein said polypeptide molecule is attached to said scaffold molecule by at least three covalent bonds and wherein the inhibition constant (Ki) for said inhibitor is less than 500nM.

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