Disclosed herein are 1,4-naphthoquinone analogs, pharmaceutical compositions that include one or more of such 1,4-naphthoquinone analogs, and methods of treating and/or ameliorating diseases and/or conditions associated with a cancer, such as prostate cancer with such 1,4-naphthoquinone analogs. Also included are combination therapies wherein a 1,4-naphthoquinone analog disclosed herein, and a hormone therapy agent are provided to a subject suffering from a condition such as cancer.Linvention concerne des analogues de 1,4-naphtoquinone, des compositions pharmaceutiques qui comprennent un ou plusieurs de ces analogues de 1,4-naphtoquinone, et des méthodes de traitement et/ou damélioration de maladies et/ou détats associés à un cancer, tels que le cancer de la prostate, au moyen de ces analogues de 1,4-naphtoquinone. Linvention porte en outre sur des thérapies de combinaison, un analogue de 1,4-naphtoquinone de la présente invention et un agent dhormonothérapie étant procurés à un sujet souffrant dune affection, telle que le cancer.
