Thomas Urbig,Thomas Boehm,Wolfram Steinhilber,Michael Molhoj
申请号：
US15922777
公开号：
US20180207278A1
申请日:
2018.03.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to aqueous formulations comprising a compound neutralizing GM-CSF in concentrations of at least about 20 mg/ml, a tonicity modifier and a buffer, wherein the composition is stable. The ingredients of the formulation preferably provide stability to the compound neutralizing GM-CSF in view of long-term storage. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory and autoimmune disorders, preferably including allergic and psoriatic disorders, as well as arthritic and asthmatic disorders. Furthermore, a kit comprising the formulation of the invention is provided.
