Zhang, Jimmy Z.,Rutter, William J.,Calos, Michelle P.
申请号:
AU2007254508
公开号:
AU2007254508B2
申请日:
2007.05.22
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The subject invention provides a site-specific integration system and methods for generating eukaryotic cells lines for protein production. The provided system includes a first site-specifically integrating target vector and a second site- specifically integrating donor vector comprising a gene of interest. Also provided are mammalian cell lines produced by the subject methods and systems, as well as kits that include the subject systems.