An animal protective device and methods of making and using it are disclosed for restraining and injecting an animal. The device includes a semi-rigid rectangular panel including a handle and a plurality of holes that are substantially centered on the panel. The device further includes a skirt attached to the rear of the panel and disposed around its circumference. In an embodiment, the holes are configured such that approximately half of the holes are arranged in a semi-circular arc on one side of the handle and the remaining holes are arranged in a semi-circular arc on the opposite side of the handle.