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Substituted indazoles, processes for their Preparation and Pharmaceutical Preparations Containing them
专利权人:
BAYER PHARMA AKTIENGESELLSCHAFT
发明人:
ALEXANDRA DR. RAUSCH,ANDREAS DR. SUTTER,CHRISTIAN DR. STEGMANN,MARTIN DR. LANGE,HOLGER DR. STEUBER,JUDITH DR. GNTHER,ULF DR. BMER,REINHARD DR. NUBBEMEYER,NICOLE DR. SCHMIDT,HOLGER DR. SIEBENEICHER,ULR
申请号:
ARP150103876
公开号:
AR102827A1
申请日:
2015.11.26
申请国别(地区):
AR
年份:
2017
代理人:
摘要:
1. This request relates to the replacement of housing, preparation procedures, use alone or in combination for the treatment and / or prevention of diseases, and drugs for the preparation of treatment and / or prevention of diseases, In particular, it is used for the treatment and / or prevention of endocrine disorders of the uterus and pain and other endocrine related symptoms of the uterus, such as deoxygenation, unusual, desulfuration and dislocation, lymphoma, rheumatoid arthritis, cavernous disorders (especially psychosis and bechterw's disease),lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver diseases, insulin insufficiency, tumor diseases and psoriasis. Claim 1: Compounds the general formula (1) wherein: R¹ represents C₁₋₆ alkyl,wherein the C₁₋₆ alkyl radical is not substituted or is mono- or polysubstituted, the same or different with halogen, hydroxy, an unsubstituted C₃₋₆ cycloalkyl or mono- or polysubstituted with halogen, a radical R⁶,R⁷SO₂,R⁷SO or R⁸O or represents a compound selected from the group of formulas (2) where * represents a site of union of the group with the radical of the molecule; R² and R³ always have the same meaning and at the same time represent hydrogen or C₁₋₆ alkyl;R⁴ represents halogen, cyano, unsubstituted or mono- or polysubstituted C₁₋₆ alkyl, the same or different from each other or unsubstituted C mono or mono- or polysubstituted cycloalkyl, the same or different from each other,e. Alternatives were selected from the halogen and hydrogen Xi groups; r83099 for hydrogen, halogen or c83218c83316262 for monkeys or PBDEs that were not replaced or were not replaced by halogen; r8310 for a single ring saturated cycle that was not replaced, or a single ring - or four to six atom formic acid that contains heteroatoms or a ring; a. Heterosexuality of O, s, so and so series;R⁷ represents C₁₋₆ alkyl,wherein the C₁₋₆ alkyl radical is not substituted or is mono- or polysubstituted, the same or differen
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