吡唑化合物

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专利权人:

ASTELLAS PHARMA INC.

发明人:

MASUDA, NAOYUKI,增田直之,MIYAMOTO, SATOSHI,宫本聪,宮本聰,KIKUCHI, SHIGETOSHI,菊池重俊,SAMIZU, KIYOHIRO,三水清宽,三水清寬,SATO, FUMIE,佐藤史惠,SHIINA, YASUHIRO,椎名康裕,HAMAGUCHI, WATARU,滨口涉,濱口涉,SEO, RYUSHI,濑尾龙志

申请号：

TW101111438

公开号：

TW201302730A

申请日:

2012.03.30

申请国别(地区):

TW

年份:

2013

代理人:

摘要：

To provide a compound useful for the prevention of and/or as a therapeutic agent for schizophrenia, anxiety, Huntington's disease, drug dependence, and/or Alzheimer's disease. The inventors studied compounds having PDE10A inhibitory actions, and confirmed that a pyrazole compound has PDE10A inhibitory actions, thus resulting in the present invention. This pyrazole compound has PDE10A inhibitory actions, and can be used for the prevention of and/or as a therapeutic agent for schizophrenia, anxiety, Huntington's disease, drug dependence, and/or Alzheimer's disease.本發明提供作為精神分裂症、焦慮症、亨丁頓舞蹈症、藥物依存、及/或阿茲海默病之預防及/或治療劑為有用的化合物。作為該解決方法為，本發明者們對於具有PDE10A阻礙作用之化合物進行檢討，確認吡唑化合物具有PDE10A阻礙作用而完成本發明。本發明的吡唑化合物具有PDE10A阻礙作用，可作為精神分裂症、焦慮症、亨丁頓舞蹈症、藥物依存、及/或阿茲海默病的預防及/或治療劑使用。

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/