The heteroaromatics of Formulas I: (I) is hiv reverse transcriptase inhibitor, wherein R1, R2, R3, and R4 and R5 are as defined herein. Compound of formula I and its pharmaceutically acceptable salt what inhibit hiv reverse transcriptase, prevention and treatment HIV infection, and prevention, postpone or are in progress, and treatment AIDS. Compound and its salt may be used as the ingredient in pharmaceutical composition, optionally with other antiviral agents, immunomodulator, antibiotic or vaccine combination.式I的雜芳族化合物:(I)是HIV逆轉錄酶抑制劑,其中R1,R2,R3,R4和R5如本文所定義。式I化合物及其藥學上可接受的鹽用於抑制HIV逆轉錄酶,預防和治療HIV感染,及預防,延緩發作或進展,以及治療AIDS。化合物及其鹽可以用作藥物組合物中的成分,任選地與其它抗病毒藥,免疫調節劑,抗生素或疫苗組合。