Process for the preparation of 3-amino-8-(1-piperazinyl)-2H-1-benzopyran-2-one and salts and solvates thereof

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专利权人:

Cornelis Bakker

发明人:

Cornelis Bakker

申请号：

US12829554

公开号：

US08173660B2

申请日:

2010.07.02

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention relates to a novel process for the preparation of 3-amino-8-(1-piperazinyl)-2H-1-benzopyran-2-one, a broad spectrum 5-HT receptor binding ligand having potent 5-HT1A-agonistic as well as 5-HT1D-antagonistic activity. The invention also relates to novel salts and solvates, in particular hydrates of salts of said compound, as well as to their use as medicaments.

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