Includes an extraction unit that extracts first information on a physiological state of a subject and second information on at least one of an emotion and organ activity of the subject from information on a physiology of the subject a calculation unit that obtains a degree of similarity between changes over time indicated by the first information and the second information which are extracted and calculates a shift amount from a predetermined state in which a homeostasis in the subject is maintained based on the obtained degree of similarity and an estimation unit that estimates a pathology of the subject based on the calculated shift amount.