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Oseltamivir phosphate granule and preparation method thereof
专利权人:
Song Li
发明人:
Song Li,Wu Zhong,Junhai Xiao,Yunde Xie,Xingzhou Li,Hao Cui,Zhibing Zheng
申请号:
US12225935
公开号:
US09034382B2
申请日:
2006.08.11
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to an oseltamivir phosphate granule and preparation method thereof. The said granule comprises 1.97-19.8 wt. % oseltamivir phosphate, 75.0-97.5 wt. % diluent, 0.1-5.0 wt. % binder, optionally 1.0-5.0 wt. % edible flavoring essence, sweetener and/or edible pigment. It is prepared by using 30-55 v/v % aqueous ethanol solution as moistening agent. The granules prepared by the formulation and method according to the present invention have good uniformity and stability and are water-soluble. The administration dosage of the granules can be conveniently selected based on the age and body weight of patients. The oseltamivir phosphate granule is suitable for administering to old people, children and flu gravis patients and those patients that swallow inconveniently or difficulty. The preparation of the granule is simple and low in production cost.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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