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ANTI-CD3-ANTIKÖRPER, ANTI-CD123-ANTIKÖRPER UND BISPEZIFISCHE, SPEZIFISCH AN CD3 UND/ODER CD123 BINDENDE ANTIKÖRPER
专利权人:
SANOFI
发明人:
ALBRECHT, Jana,BARRIERE, Cédric,BEIL, Christian,BENINGA, Jochen,CARREZ, Chantal,GUERIF, Stéphane,KROLL, Katja,LANGE, Christian,LEMOINE, Cendrine,LEUSCHNER, Wulf-Dirk,RAO, Ercole,SCHNEIDER, Marion,WETZ
申请号:
EP16701353
公开号:
EP3247725B1
申请日:
2016.01.22
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention concerns antibody-like binding protein specifically binding to CD3 and binding specifically to at least one further antigen, for example CD123. The present invention also concerns antibody-like binding protein specifically binding to CD123 and binding specifically to at least one further antigen. The invention further concerns anti-CD3 antibodies and anti-CD123 antibodies. The invention also relates to pharmaceutical compositions comprising the antibody-like binding protein, anti-CD3 antibodies or anti-CD123 antibodies of the invention, and their use to treat cancer. The invention further relates to isolated nucleic acids, vectors and host cells comprising a sequence encoding said antibody-like binding protein, anti-CD3 or anti-CD123 antibody and the use of said anti-CD123 antibody as a diagnostic tool.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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