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Crystalline forms of substituted pyrazolopyrimidines
专利权人:
MERZ PHARMA GMBH & CO. KGAA
发明人:
PLITT, PATRICK,HAUPTMEIER, BERNHARD,BODERKE, PETER
申请号:
AU2010323209
公开号:
AU2010323209A1
申请日:
2010.11.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to novel co-crystals of pyrazolopyrimidines and a co-crystal former, wherein the co-crystal former is an organic carboxylic acid, preferably selected from the group of gentisic acid, succinic acid and xinafoic acid. The pyrazolopyrirnidkes, and in particular compound A are potent mGluR5 modulators and are useful for the prevention and treatment of acute and chronic neurological disorders, in particular CNS (central nervous system) disorders, which involve excessive glutamate induced excitation.
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