COMPOSITION FOR SKIN WHITENING COMPRISING (3R)-5-&lsqb；&lsqb；(2R,3S,4R,5R,6S)-6-&lsqb；2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-4-OXO-CHROMEN-8-YL&rsqb；-3,4,5-TRIHYDROXY-TETRAHYDROPYRAN-2-YL&rsqb；METHOXY&rsqb；-3-HYDROXY-3-METHYL-5-OXO-PENTANOIC ACID AS EFFECTIVE COMPONENT AND USES THEREOF
KIM, EUN KI,김은기,LEE, HYANG BOK,이향복,LEE, SHIN AE,이신애,SHIN, JAE MIN,신재민,LEE, JI YOUNG,이지영,DO, KYOUNG ROK,도경록,KIM, EUN KIKR,LEE, HYANG BOKKR,LEE, SHIN AEKR,SHIN, JAE MINKR,LEE, JI YOUNGKR,DO, KYOUNG ROKKR
申请号：
KR1020140085317
公开号：
KR1015734200000B1
申请日:
2014.07.08
申请国别(地区):
KR
年份:
2015
代理人:
摘要：
The present invention relates to a composition for skin whitening and uses thereof. A (3R)-5-[[(2R,3S,4R,5R,6S)-6-[2-(3,4-dibydroxyphenyl)-5,7-dihydroxy-4-oxo-chromen-8-yl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]methoxy]-3-hydroxy-3-methyl-5-oxo-pentanoic acid compound with an excellent suppression effect on melanin generation has almost no cell toxicity, so as to be usefully used as an active ingredient of a cosmetic composition for skin whitening, a health food composition, and a pharmaceutical composition.본 발명은 피부 미백용 조성물 및 이의 용도에 관한 것으로, 우수한 멜라닌 생성 억제 효과를 나타내는 (3R)-5-[[(2R,3S,4R,5R,6S)-6-[2-(3,4-디하이드록시페닐)-5,7-디하이드록시-4-옥소-크로멘-8-일]-3,4,5-트리하이드록시-테트라하이드로피란-2-일]메톡시]-3-하이드록시-3-메틸-5-옥소-펜타노익엑시드 화합물은 세포 독성이 거의 없으므로, 피부 미백용 화장료 조성물, 건강식품 조성물 및 약학 조성물의 유효성분으로 유용하게 사용될 수 있다.
