PROBLEM TO BE SOLVED: To provide a scaffold to be used in cell transplantation treatment to a cartilage defect or the like.SOLUTION: A new scaffold, for which a porous polymer is coated with an extracellular matrix derived from amniotic cells, is developed. The scaffold can sufficiently demonstrate the effect of components of the extracellular matrix derived from the amniotic cells, and is highly useful in regeneration of living tissue such as the repair of a cartilage defect.COPYRIGHT: (C)2014,JPO&INPIT【課題】軟骨欠損に対する細胞移植治療などに用いる足場(スキャホールド)を提供すること。【解決手段】羊膜細胞由来の細胞外マトリックスを多孔質ポリマーにコーティングした新規なスキャホールドを開発した。このスキャホールドは、羊膜細胞由来の細胞外マトリックスの含有成分の効果を十分に発揮させることでき、軟骨欠損の修復など生体組織の再生おいて有用性が高い。【選択図】図6