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Selective targeting of the CD40L/Mac-1 interaction by small peptide inhibitors and its use for the treatment of inflammation and atherogenesis
专利权人:
Baker IDI Heart & Diabetes Institute Holdings Ltd.;Universitatsklinikum Freiburg
发明人:
Zirlik, Andreas,Wolf, Dennis,Peter, Karlheinz
申请号:
AU2011317807
公开号:
AU2011317807A1
申请日:
2011.08.17
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The CD40L/Mac-1 interaction is selectively targeted by small peptide inhibitors and/or antibodies and such peptides are used for the specific treatment of inflammation and atherogenesis. In particular, pharmaceutical compositions comprising a polypeptide having the amino acid sequence EQLKKSKTL and antibodies specifically binding to an epitope are disclosed.
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